Olfactory Memory Impairment in Neurodegenerative Diseases

Olfactory memory impairment in neurodegenerative diseases.

Olfactory disorders are noted in a majority of neurodegenerative diseases, but they are often misjudged and are rarely rated in the clinical setting. Severe changes in the olfactory tests are observed in Parkinson's disease. Olfactory deficits are an early feature in Alzheimer's disease and they worsen with the disease progression. Alterations in the olfactory function are also noted after seve...

Olfactory Dysfunction in Neurodegenerative Diseases

INTRODUCTION Olfactory impairment is a common occurrence in aging and may be an early signal of neurodegenerative diseases. Olfactory loss caused by aging and diseases affects both quality of life and personal safety. Aging, as well as viral infections, neurodegenerative diseases, head injuries, chronic sinusitis infections and nasal obstructions are the most common causes of olfactory disorder...

Calculation impairment in neurodegenerative diseases.

We examined oral calculation in patients with corticobasal degeneration (CBD; N=17), frontotemporal dementia (FTD; N=17), and Alzheimer's disease (AD; N=20), as well as 17 healthy seniors matched for age and education. Our calculation model involves at least three components: numerosity, combinatorial processes, and executive resources such as working memory. We assessed addition, subtraction, ...

Neurodegenerative Diseases and Olfactory Dysfunction

The olfactory sensory network is a unique brain system. Among human sensory systems, only olfaction has a direct connection to the brain and no thalamic relay. In terms of tissue and cellular repair, the olfactory system is unusual, along with the hippocampal dentate gyrus, as an example of central nervous tissue in which neurogenesis persists. Additionally, olfaction has been shown to have an ...

Clinical importance of olfactory function in neurodegenerative diseases